Residence Inn By Marriott Durham Duke University Medical Center Area | City stay in Durham | Book Now

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About the Hotel

1108 West Main Street, Durham, North Carolina, United States, 27701

Spacious Suite Accommodations

Residence Inn Durham offers 147 air-conditioned suites with separate living, cooking, and sleeping areas. Each suite includes a full kitchen with a stovetop, full-sized refrigerator/freezer, dishwasher, and cookware. Rooms feature ergonomic workstations, free Wi-Fi, and private bathrooms with showers or baths. Select suites include a seating area and sofa bed.

Complimentary Breakfast Daily

Guests receive a free full American hot breakfast served daily. For other meals, each suite's kitchen allows for self-catering. Grocery delivery service is available for ingredients. The hotel hosts a complimentary reception with snacks and drinks on select days.

Indoor Pool and Fitness

The hotel features an indoor heated pool and a 24-hour fitness center with cardio equipment and free weights. The property includes a fireplace in the lobby and offers grocery deliveries, luggage storage, and meeting facilities.

Near Duke University

Located in Downtown Durham, the hotel is near Duke University, North Carolina Central University, and Durham Performing Arts Center. It is 1 mile from Durham Bulls Athletic Park, 1.5 miles from American Tobacco Historic District, and 11.5 miles from University of North Carolina. The complimentary area shuttle serves nearby destinations with 24-hour advance reservation.

Business and Guest Services

The hotel provides 2,528 square feet of meeting space across five venues with AV equipment. Services include express check-in/check-out, a business center, wedding services, dry cleaning, and mobile key access. The property is pet-friendly with fees starting at $100 for 1-7 days and offers wheelchair-accessible rooms and facilities.

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Choose the Room

From cosy doubles to spacious family suites – all with flexible options, breakfast, and exclusive deals.

King Studio

Max:

2 persons

485 sq. feet

Coffee machine

Heating

room details

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Queen Studio Sofa Bed

Max:

2 persons

435 sq. feet

Coffee machine

Heating

room details

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One-Bedroom Suite

Max:

2 persons

475 sq. feet

Coffee machine

Heating

room details

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Check Dates & Room Rates

See what's available for your travel dates

Getting around

All Transportation Options at a Glance

City Centre

Durham5000 ft

Airports

Raleigh-Durham International (RDU) 15.5 mi

Danville Regional (DAN) 56.9 mi

Amenities

Thoughtfully designed amenities for a comfortable & memorable stay

Free Wi-Fi

Parking

USD 15 per day

Luggage storage

24-hour services

24-hour reception

General

No smoking on site
Free Wi-Fi
On-site car park
Handicap parking
Safe deposit box
24-hour reception
Express check-in/ -out
Pets allowed
Rooms/ Facilities for disabled
Wheelchair access
Security
Luggage storage
Lift
Fireplace
Smoke detectors
Fire extinguishers
Key card access
Key access

Sports & Fitness

Fitness centre

Guest Parking

Cookware/ Kitchen utensils

Services

Free shuttle service
Car hire
Laundry
Dry cleaning
Grocery shopping service
Shops/Commercial services

Dining

Bar/ Lounge area
Picnic area/ Tables

Business

Business centre
Meeting/ Banquet facilities
Fax/Photocopying

Spa & Leisure

BBQ facilities
Leisure/ TV room

Room features

Air conditioning
Heating
Sitting area
Terrace
Garden furniture

Self-catering

Cookware/ Kitchen utensils

Location

1108 West Main Street, Durham, North Carolina, United States, 27701

Map view

1108 West Main Street, Durham, North Carolina, United States, 27701

City landmarks

Garden

Sarah P. Duke Gardens

1.6 mi

Landmark

American Tobacco Campus

4800 ft

Church

Duke University Chapel

1.5 mi

Landmark

Durham Bulls Athletic Park

1.1 mi

Park

Durham Central Park

4000 ft

Landmark

American Tobacco Historic District

4700 ft

Museum

Nasher Museum of Art

1.3 mi

Museum

Museum of Life and Science

2.0 mi

Museum

Museum of Durham History

2700 ft

Landmark

Historic Durham Athletic Park

4100 ft

Event hall

Durham Performing Arts Center

5200 ft

Event hall

Durham Convention Center

3800 ft

Landmark

Golden Belt Historic District

3000 ft

Market

Durham Farmer's Market

4000 ft

Church

Duke Memorial United Methodist Church

2300 ft

Landmark

Durham Distillery

3900 ft

Landmark

Carolina Theatre

3300 ft

Landmark

Community Outreach Partnership

2200 ft

Landmark

Wallace Wade Stadium

1.7 mi

Landmark

Ar-Razzaq Islamic Center

2300 ft

Landmark

Pauli Murray Center for History and Social Justice

3700 ft

Church

Trinity Avenue Presbyterian Church

2500 ft

Landmark

The History Hub Museum

2500 ft

Landmark

Imperial Tobacco

2500 ft

Nearby

Bridge

11 foot 8 Bridge

1200 ft

North Carolina Eye & Ear Hosp

500 ft

Bridge

11'8"

1200 ft

Christian and Missionary Alliance Community Church

1200 ft

Church

Immaculate Conception Catholic Church

1200 ft

Duke University Museum of Art

1800 ft

Restaurants

Papa John's

700 ft

1018 W Main St

Toast

3200 ft

345 West Main Street

King's Sandwich Shop

4100 ft

701 Foster Street

Cocoa Cinnamon

4200 ft

420 West Geer Street

Guest Ratings & Reviews

Real Guest Experiences & Ratings

Dorothy

United States, January 2024

8.4/10

I had a wonderful stay at this hotel. The rooms were spotless and had everything we needed, though they felt a bit tight when the sofa bed was out. The layout was nice and large, divided into a sitting area, kitchenette, and sleep area. The service was fantastic, with friendly and accommodating staff who went out of their way to make our group feel taken care of. The location was perfect, allowing us easy access to Duke University and downtown Durham. The dining experience was good overall, with some limited food choices during our stay. The facilities were well-maintained and added to the comfort of our visit.

Rooms

8.0

The rooms were spotless and had everything we needed, though they felt a bit tight when the sofa bed was out. The layout was nice and large, divided into a sitting area, kitchenette, and sleep area.

Service

9.0

The staff was friendly and accommodating, making our group feel welcome and taken care of.

Location

9.0

The location was very convenient, close to Duke University and downtown Durham, making it easy for us to get around. The free shuttle service was a great added perk.

Dining

7.0

The dining experience was decent, with good offerings overall during our stay.

Facilities

9.0

The facilities were well-maintained and added to the overall comfort of our stay.

Thomas

United States, December 2023

7.8/10

I had a pleasant stay overall at this hotel. The rooms were clean and comfortable, although a bit noisy from the bar across the street. The location was extremely convenient, close to Duke East Campus and Main Street Durham. The service was top-notch, very friendly and accommodating. The dining experience was decent, but could use some improvement in menu variety.

Rooms

7.0

The rooms were more spacious than expected and well laid out.

Service

9.0

The service was extremely friendly and helpful, especially when we needed assistance for a large group.

Location

9.0

The hotel's location was very convenient for our Duke University-based meetings and exploring the Duke Medical Center area.

Dining

6.0

The dining options were fairly sparse, but the staff was attentive to keeping things tidy.

Facilities

8.0

The hotel offered a variety of services such as car hire and laundry, which was convenient for guests.

Johnny

United States, October 2023

8.6/10

My stay at the hotel was fantastic! The rooms were clean and comfortable, and the staff was super friendly. The location is perfect, close to Duke University and downtown Durham. The dining experience was good, although the breakfast ended a bit early for my taste. The facilities were well-maintained and enjoyable.

Rooms

9.0

The rooms were clean, comfortable, and well-appointed with a full kitchen.

Service

9.0

The staff was so friendly and accommodating, always going out of their way to greet us and handle special requests.

Location

9.0

The hotel's location near Duke's East Campus and with a free shuttle service made it easy for me to get around. Plus, being close to downtown Durham was a bonus.

Dining

8.0

The dining experience was good with friendly service, but I wish the breakfast hours were a bit longer.

Facilities

8.0

The facilities were well-maintained, and the exercise room was a nice addition.

Charles

United States, August 2023

8.2/10

The hotel was extremely comfortable and clean. Although facing the street made it challenging due to noise, I couldn't avoid it again. The service was top-notch with staff going out of their way to greet us and handle special requests. The location was very convenient for our Duke University-based meetings and exploring Durham. However, the dining options were fairly sparse and limited in variety, forcing us to seek alternatives.

Rooms

7.0

The room took forever to cool down but was extremely comfortable and clean.

Service

9.0

The staff was extremely friendly and helpful, going above and beyond our expectations.

Location

9.0

The location was excellent, particularly for Duke-related activities and exploring Durham.

Dining

5.0

The dining experience was dreadful with very limited and unhealthy choices available.

Facilities

8.0

The hotel offers convenient car hire and laundry services.

Craig

United States, June 2023

9.2/10

I stayed at this hotel and had a fantastic experience. The rooms were spotless and had everything I needed, including beautiful new quartz countertops, a fridge, microwave, and a luxurious bed with great linens and pillows. The room felt a bit tight when the sofa bed was out, but it was super clean, and the staff was friendly. The great breakfast bar down the street was a bonus.

Rooms

9.0

The room was spotless and had everything I needed. The bed was luxurious with great linens and pillows.

Service

10.0

The staff was friendly and accommodating. They went out of their way to make my stay enjoyable.

Location

10.0

The hotel's location was walkable and a great place to visit, very convenient to Duke East Campus, Main Street Durham restaurants, groceries, and attractions, and Duke Medical Center.

Dining

8.0

The dining experience was above average with varied and tasty options. The staff was friendly and efficient at maintaining the breakfast items.

Facilities

9.0

The facilities were well-maintained, and I particularly enjoyed the exercise room.

James

United States, May 2023

7.8/10

The hotel's rooms are fresh and comfortable, offering spacious accommodations with convenient amenities like a microwave, stove top, cooking utensils, and a full refrigerator. However, the room's proximity to the street can be a bit noisy at times, waking me up a couple of times at night.

Rooms

8.0

The rooms are fresh and comfortable and quite large with essential kitchen facilities.

Service

9.0

The service was always friendly and professional, and the staff was eager to assist. I appreciated being assigned a quiet room overlooking the parking lot on the back side of the building.

Location

7.0

The location is very convenient, close to Duke University and downtown Durham, offering a homey feel. However, it may present challenges for those with mobility issues.

Dining

7.0

The dining experience was good, with a decent selection and attentive staff. It's a shame there weren't more healthy options available at all times.

Facilities

8.0

The hotel offers various essential services like car hire, dry cleaning, and a grocery shopping service.